| From $50 to $99 |
| COMFORT INN WYTHEVILLE | 315 HOLSTON RD, Wytheville, Virginia |
| BUDGET HOST INN WYTHEVILLE | 705 CHAPMAN ROAD, Wytheville, Virginia |
| ECONO LODGE WYTHEVILLE | 1160 E MAIN ST, Wytheville, Virginia |
| RAMADA INN | 955 PEPPERS FERRY RD, Wytheville, Virginia |
| BW WYTHEVILLE INN | 355 NYE ROAD, Wytheville, Virginia |
| DAYS INN WYTHEVILLE | 150 MALIN DR, Wytheville, Virginia |
| QUALITY INN AND SUITES WYTHEVIL | 2015 E MAIN STREET, Wytheville, Virginia |
| HOLIDAY INN WYTHEVILLE | US11 I81 AND I77, Wytheville, Virginia |
| HAMPTON INN WYTHEVILLE | 1090 PEPPERS FERRY, Wytheville, Virginia |
| SLEEP INN WYTHEVILLE | 135 NYE CIRCLE, Wytheville, Virginia |
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